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Such cancers typically develop 10 or more years after exposure to radiation. Data from studies in animals suggest that oxidative damage from factors such as smoking or gastroesophageal reflux, which cause inflammation, esophagitis, and increased cell turnover, may initiate the carcinogenic process. Radiotherapy The use of primary radiotherapy as an alternative to surgery was initially evaluated in patients with squamous-cell carcinomas of the esophagus whose general medical condition made them poor operative candidates. As recently asabout 75 percent of cases of esophageal cancer diagnosed in the United States were squamous-cell carcinomas and the remaining 25 percent were adenocarcinomas.

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Ask or add my snap @nrnate152 I'm here to meet new people. Incidence Cancers arising from the esophagus, including the gastroesophageal junction, are relatively uncommon in the United States, with 13, new cases and 13, deaths anticipated in Such cancers typically develop 10 or more years after exposure to radiation.
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Alternative forms of systemic treatment that incorporate a taxane, irinotecan, or a targeted form of treatment e. A randomized study involving North American patients showed no benefit, with 35 percent of patients in the chemotherapy-plus-surgery group alive after two years as compared with 37 percent of patients in the surgery-alone group. During the past 20 years, for as-yet-unexplained reasons, the incidence of squamous-cell carcinomas has decreased in both the black population and the white population particularly among men , while the rate of adenocarcinoma has increased by percent among white men and 50 percent among black men.
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